BIOACTIVE

Riley D. Kirk, Ph.D.
BIOACTIVE
Neueste Episode

82 Episoden

  • BIOACTIVE

    Cannabis and Traumatic Brain Injuries with guest Nikki Lawley

    20.03.2026 | 58 Min.
    Dr. Riley Kirk welcomes Nikki Lawley to the podcast
    to discuss the transformative role of medical cannabis in managing traumatic
    brain injury (TBI), sharing her powerful personal journey alongside practical
    insights into cannabis as medicine. They cover topics such as the immediate and
    long-term symptoms of TBI, the challenges of navigating traditional healthcare
    systems, and the limitations of pharmaceutical treatments. Additionally, they
    explore how cannabis became a turning point in Nikki’s recovery, the barriers
    to access in the United States, and the stigma patients face when seeking
    alternative therapies. The discussion emphasizes patient-centered care, the
    importance of advocacy, and the growing role of cannabis in treating
    neurological conditions.

    They also delve into various aspects of cannabis science and
    personalized medicine, including cannabinoid therapy, terpene profiles, and the
    use of data tracking tools like Strainprint to optimize treatment outcomes.
    They discuss the significance of consistency in dosing, the effects of aged
    cannabis and CBN, and the role of terpene boiling points in consumption
    methods. The conversation further explores different delivery systems such as
    vaping and inhalation, how cannabis interacts with the endocannabinoid system,
    and the importance of experimentation in finding effective protocols. Finally,
    they touch on cannabis policy, patient advocacy, and the critical role of
    storytelling in advancing legalization and improving access for patients
    worldwide.

    This is a conversation for anyone navigating chronic
    illness, traumatic brain injury, or exploring cannabis as a potential
    therapeutic option. Whether you're a patient, caregiver, healthcare
    professional, or simply curious about the science of cannabinoids and the
    endocannabinoid system, this episode provides valuable insights into how
    cannabis can be used intentionally to support healing and improve quality of
    life.

     

    Chapters

    00:00 TBI Changed Everything
    01:34 Podcast Intro And Mission
    02:37 The Headbutt Incident
    05:10 Symptoms Hit Fast
    06:48 Pharma Spiral And Workers Comp
    10:49 Vegas Breakdown And Billboard Sign
    16:44 First Cannabis Relief
    19:40 Back Home Stigma And Barriers
    23:18 Medical Cannabis Refuge In Canada
    25:00 Strainprint Data And Terpene Tracking
    29:32 Canada Trips And Building A Routine
    31:33 Aged Flower and CBN
    32:23 Terpene Boiling Points
    33:24 L Orange Strain Deep Dive
    35:33 Growing Pains and Pests
    37:26 CB2 Targets and Nose Testing
    39:13 Vapes Metabolism and ECS Tests
    42:08 Myrcene Blue Lobster Effects
    43:48 Cannabis vs Pills After TBI
    49:07 Advocacy and Policy Reality
    53:12 Consumption Methods and Work
    56:50 Wrap Up and Where to Find

    Connect with Nikki Lawley

    Follow Nikki Lawley for insights on medical cannabis,
    traumatic brain injury (TBI), patient advocacy, and cannabinoid education:

    Website: nikkiandtheplant.org
    Instagram and Facebook: @nikkiandtheplant
    LinkedIn: Nikki Lawley

     

    Want Exclusive Content and Ad-Free Episodes?

    Join the Bioactive Patreon community for as little as
    $1/month to ask guests your burning questions, access exclusive content, and
    connect with Dr. Kirk one-on-one.
    www.Patreon.com/Cannabichem

    🔔 Don’t forget to like,
    subscribe, and hit the notification bell for more expert insights into cannabis
    science, pharmacology, plant medicine, and natural products.

     

    Sign Up for Emails

    www.AppliedPharmacognosy.org

     

    Keep Up with Dr. Riley Kirk
    YouTube: Cannabichem
    IG: Bioactive Podcast

    Website: www.bioactivepodcast.com/
    , www.appliedpharmacognosy.org/
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  • BIOACTIVE

    Beyond Caffeine: The Hidden Chemistry of Coffee with Dr. Steven Helschien (Dr. Coffee)

    06.03.2026 | 1 Std. 9 Min.
    There are all sorts of misconceptions about coffee — that it dehydrates you, that it’s bad for your heart, or that caffeine is the only thing happening in the cup.

    Dr. Riley Kirk welcomes coffee scientist Dr. Steven Helschien, widely known as “Dr. Coffee,” for a fascinating conversation exploring the chemistry, health effects, and cultural significance of one of the world’s most widely consumed psychoactive plants: coffee. With a background in chemistry and extensive experience in coffee education and research, Dr. Helschien breaks down the complex science behind coffee in a way that is both practical and accessible.

    They discuss coffee as a psychoactive plant medicine, examining not only caffeine but also the wide range of entourage compounds that influence its physiological and cognitive effects.

    Dr. Helschien and Dr. Kirk explore coffee’s relationship with inflammation, liver health, and cardiovascular markers, unpacking what current research suggests about coffee consumption and long-term wellness. They also explore the importance of coffee quality, including concerns about mold contamination, sourcing practices, and what consumers should look for when choosing high-quality beans. The conversation touches on brewing techniques and the science of extraction, the chemistry behind decaffeination methods, and why caffeine affects the body the way it does.
    The episode also expands into broader discussions about coffee as plant medicine, the cultural role of caffeine, and the fine line between daily ritual and dependence.
    Dr. Helschien shares insights into mold-free coffee sourcing, considerations around caffeine and breastfeeding, and practical strategies like caffeine cycling to maintain sensitivity to its effects.

    This is a conversation for anyone who loves coffee but wants to understand what’s really happening in the cup. Whether you're curious about caffeine’s effects, confused by common coffee myths, exploring brewing methods, or simply trying to get more out of your daily ritual, this episode offers science-backed insight in an accessible way. From the chemistry of flavor and roasting to the physiology of caffeine and the cultural habits surrounding coffee, Dr. Helschien helps demystify one of the world’s most widely consumed beverages.

    Episode Chapters:
    01:02 Meet Dr Coffee
    02:08 Psychoactive Plant
    03:04 Entourage Compounds
    06:04 Inflammation And Liver
    08:19 Quality And Mold
    10:13 Brain Heart Plaque
    23:43 Brewing And Decaf
    35:43 Decaf Methods Explained
    36:49 Why Caffeine Works
    38:36 Coffee as Plant Medicine
    39:39 Coffee Addiction and Culture
    43:12 Mold Free Coffee Buying
    45:49 Breastfeeding and Caffeine
    47:20 Caffeine Cycling Hack
    59:15 Community Q&A and Wrap Up

    Get Free Coffee Science Resource from Dr. Helschien:
    [email protected]

    Connect with Dr. Helschien:
    LinkedIn - Dr. Steven Helschien

    Want Exclusive Content and Ad-Free Episodes?
    Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.
    www.Patreon.com/Cannabichem

    🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, pharmacology, and plant-based medicine!

    Sign Up for Emails
    www.AppliedPharmacognosy.org

    Keep Up with Dr. Riley Kirk
    https://www.bioactivepodcast.com/
    https://www.youtube.com/@cannabichem
    https://instagram.com/cannabichem
    https://www.appliedpharmacognosy.org/
    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • BIOACTIVE

    How Fast-Acting Products Actually Work with Harold Han, PhD

    20.02.2026 | 57 Min.
    Dr. Riley Kirk welcomes Dr. Harold Han, Chief Science Officer and Co-Founder of Vertosa to explore the fascinating world of the science powering modern cannabis beverages and infused products. Known in
    the industry as “The Happy Chemist,” Dr. Han explains how emulsion technology solves the classic oil-and-water problem that makes cannabinoids difficult to incorporate into drinks. The conversation breaks down how water-compatible cannabinoids are created, why droplet size and consistency matter for potency and onset, and how stability challenges differ between beverages and gummies.

    They explore oxidation rates of major cannabinoids, packaging risks like
    “scalping” from can liners, and new patented approaches to preserving potencyin infused drinks.

    They also examine the full beverage development pipeline, from cannabinoids and infusion technology to formulation, manufacturing,
    testing, and distribution, highlighting the many points where potency and
    quality can be affected. Dr. Han clarifies the difference between nano and
    micro emulsions, why most commercial cannabis drinks use nano systems, and how natural emulsifiers influence formulation choices. The discussion further explores how the human body processes emulsified cannabinoids, why food (especially fat) changes edible effects, and how fast-acting beverages work at a physiological level. They discuss new human research initiatives, patient applications such as consistent dosing without sugar or smoke, and how standardized emulsions could transform both clinical research and at-home use.

    Looking ahead, Dr. Han shares insights on full-plant formulations, the future of cannabis as a precise delivery system for medicine, and the role of science-driven innovation in making cannabinoids more accessible, consistent, and scalable across recreational, wellness, and medical markets.

    Chapters

    00:00 Welcome + Meet Dr. Harold Hahn (“Happy Chemist”) & What Vert Does

    00:52 From Cannabis Stigma to Conscious Living: Harold’s Personal Journey

    02:18 The Oil-and-Water Problem: Emulsifiers Explained for Cannabis Drinks

    04:13 Vert’s Water-Compatible Cannabinoids: Droplet Size, Consistency & Effects

    09:48 Stability Deep Dive: Physical Separation, Oxidation Rates & Gummies vs Beverages

    16:05 Packaging Pitfalls: Can Liners, “Scalping,” FTIR Testing & a New Patent Fix

    22:49 Beverage R&D Checklist: The 7-Step Supply Chain + Taste/Mouthfeel Priorities

    27:16 Flavor Wars: Tasteless THC vs “Tastes Like the Plant”

    28:37 Nano vs Micro Emulsions Explained (It’s Not Just Size)

    31:40 Why Most Cannabis Drinks Use Nano: Natural Emulsifiers
    & Custom Control

    34:38 Fast-Acting vs Slow-Acting: What Your Gut Does With
    Emulsions

    37:41 Food Effects + The New UCSF Cannabis Beverage PK Lab

    40:32 Patient Benefits: Consistent Dosing, No Sugar, Full-Plant Medicine

    44:23 Research, DIY Possibilities & Big-Picture Wrap-Up

     

    Connect with Dr. Harold Han

    LinkedIn: Harold Han Ph.D. (The Happy Chemist)

    Company: Vertosa — https://vertosa.com/

     

    Want Exclusive Content and Ad-Free Episodes?

    Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.
    www.Patreon.com/Cannabichem

    🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, pharmacology, and industry innovation!

     

    Sign Up for Emails

    www.AppliedPharmacognosy.org

     

    Keep Up with Dr. Riley Kirk

    https://www.bioactivepodcast.com/
    https://www.youtube.com/@cannabichem
    https://instagram.com/cannabichem
    https://www.appliedpharmacognosy.org/
    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • BIOACTIVE

    Schedule 3, Hemp Bans, and Cannabis Law with Thomas Howard

    06.02.2026 | 1 Std. 4 Min.
    In this episode of the Bioactive Podcast, Dr. Riley Kirk welcomes cannabis attorney and legalization advocate Tom Howard to unpack the complexities of cannabis law and regulation in the United States. Drawing on more than 15 years of experience, Tom shares how he helps clients navigate licensing and application processes for dispensaries and cannabis businesses across multiple states. Together, they explore how state-by-state regulatory systems function, the challenges of securing permits, and the financial barriers facing cannabis entrepreneurs, particularly social equity applicants.

    The conversation also examines the federal effort to move cannabis from Schedule I to Schedule III, discussing what rescheduling could mean for taxation, scientific research, and cannabis operations nationwide.
    Additional topics include the recent hemp ban and its impact on THCA products, seed sales, and interstate commerce, ongoing banking challenges in the cannabis industry, advocacy organizations pushing for reform, and legal strategies for remaining compliant in a shifting regulatory environment. Tom also offers insight into his work with Cannabis Legalization News before the episode closes with a forward-looking discussion on the future of legalization and cannabis policy.

    Chapters:

    00:00 Introduction to the Bioactive Podcast

    00:36 Tom Howard's Journey in Cannabis Law

    01:17 Navigating State Regulations and Applications

    03:46 Challenges and Legal Complexities

    06:24 Financial Hurdles in the Cannabis Industry

    15:13 The Impact of Federal Law and Rescheduling

    30:27 Advocacy and Future of Cannabis Legislation

    34:17 THCA and Synthetic Cannabinoids Ban

    34:41 Congressional Actions and Implications

    37:14 Banking Challenges for Cannabis Businesses

    38:53 Project 2025 and Political Climate

    40:22 Hemp Industry Loopholes and Regulations

    51:33 Cannabis Legalization News and Podcast

    55:17 Future of Cannabis Legislation

     

    Watch Cannabis Legalization News
    www.youtube.com/@CannabisLegalizationNews

    Learn more about Thomas Howard
    https://cannabisindustrylawyer.com

    Visit Collateral Base
    https://collateralbase.com

    Connect with Tom

    www.linkedin.com/in/thomas-howard-attorney

     

    Want Exclusive Content and ad-free episodes?

    Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem

    Be sure to like, subscribe, and turn on notifications for more expert conversations on cannabis science, federal policy updates, and industry trends.

    Sign Up for Emails! 

    www.AppliedPharmacognosy.org

      

    Keep up with Dr. Riley Kirk:

    https://www.bioactivepodcast.com/

    https://www.youtube.com/@cannabichem

    https://instagram.com/cannabichem

    https://www.appliedpharmacognosy.org/
    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • BIOACTIVE

    The Untapped World of Acidic Cannabinoids with Dr. Bid

    23.01.2026 | 1 Std. 12 Min.
    In this episode of the Bioactive Podcast, Dr. Hemant Bid joins Dr. Riley Kirk discussing the often-overlooked world of acidic cannabinoids aka Raw or Unactivated cannabinoids, such as CBGA, THCA, and CBDA. He shares his extensive background in cannabis research and education, emphasizing the therapeutic potential of these compounds, which are non-psychoactive and interact with various non-cannabinoid targets in the body. The conversation also delves into extraction techniques for preserving these cannabinoids, their role in plant defense, and the future of research in this area. Dr. Bid highlights the importance of personalized medicine and the need for more education and understanding in the field of medical cannabis.

    Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ www.Patreon.com/Cannabichem⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
    🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more!

    Follow Dr. Bid on LinkedIn
    https://www.linkedin.com/in/hemant-kumar-bid-bs-ms-phd-ms-pharmacology-60aabb15/
    Sign Up for Emails! 
    ⁠www.AppliedPharmacognosy.org⁠ 
    Keep up with Dr. Riley Kirk:
    ⁠⁠⁠⁠⁠https://www.bioactivepodcast.com/⁠⁠⁠⁠⁠
    ⁠⁠⁠⁠⁠https://www.youtube.com/@cannabichem⁠⁠⁠⁠⁠
    ⁠⁠⁠⁠⁠https://instagram.com/cannabichem⁠⁠⁠⁠⁠
    ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.appliedpharmacognosy.org/⁠⁠⁠⁠⁠
    Learn more about your ad choices. Visit megaphone.fm/adchoices

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Über BIOACTIVE

Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke. Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm. Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.
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