Please visit answersincme.com/860/240201346-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Shannon Salvador, MD, MSc, FRCSC; Sheila Wijayasinghe, MD, CCFP, MSCP; and Christine Palmay, HBArtSci, MD, CCFP. In this activity, experts in HPV vaccination discuss its critical role in cancer prevention, the latest guideline updates, and strategies to improve uptake in populations of interest. Upon completion of this activity, participants should be better able to: Describe the prevalence and impact of human papilloma virus (HPV) infection and its associated cancers across diverse patient populations; Explain the rationale for HPV vaccination in adolescents, including the role of publicly funded programs and current uptake trends in Canada; Explain the rationale for HPV vaccination beyond adolescence, including benefits for adults, men, and individuals in monogamous relationships; and Apply current HPV vaccination recommendations and interprofessional strategies to build confidence and improve uptake across care settings, including cervical cancer screening visits.