Masters of Scale

Mark Cuban has spent decades as a serial entrepreneur and investor, with one of the best track records on the planet (including celebrity status on ABC’s Shark Tank). In this episode of Pioneers of AI, Cuban joins host Rana El Kaliouby for a wide-ranging conversation about whether we are in an AI bubble, how he’s applying his investment philosophy to AI, and why the AI world is tending to excite him less and less each day.Learn more about Pioneers of AI: http://pioneersof.ai/Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

To get the most out of your talent, you need to create an environment that allows them to thrive. Nobody knows this better than Indra Nooyi, who spent 12 years as the CEO of PepsiCo. Her drive to support talent underpinned the initiatives that transformed the company. Hear her conversation with host Reid Hoffman in this episode from our archive.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/newsletter/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this encore episode of Rapid Response, we revisit a scientific breakthrough that set the internet ablaze: The ‘de-extinction’ of the dire wolf. While many celebrated Colossal Biosciences’ announcement, the experiment also sparked controversy throughout the scientific community — namely the ethics of birthing and re-wilding extinct animals, and whether Colossal’s dire wolf puppies are the real thing. Colossal’s co-founder and CEO Ben Lamm joined host Bob Safian to take us inside the dire wolf journey, revealing how the startup attracted a roster of celebrity investors, and what the company’s technology means for not only conservation and biodiversity, but potentially the future of human health. Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

After serving as Chief Legal Officer and then CFO at Salesforce, Amy Weaver sought a new challenge. She is now CEO of Direct Relief, which she tells host Jeff Berman is "the largest, most efficient, most effective, and most impactful global humanitarian group that you may never have heard of.” Weaver reveals scale lessons from Salesforce and how she's now applying them to amplify Direct Relief's vital work.Learn more about Direct Relief: directrelief.orgSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/newsletter/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This year delivered whiplash: geopolitics, tariffs, and technology all shifting at once. And heading into 2026, the disruption isn’t easing up. In this special episode, host Bob Safian distills five hard-won lessons from Rapid Response this year on how to lead when the ground won’t stop moving. You’ll hear standout moments from Brian Chesky, Clara Shih, Marc Lore, José Andrés, and more, with practical takeaways for turning uncertainty into advantage.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.