Possible

Carbon removal has gone from a niche climate concept to one of the world's most important challenges. Reid and Aria sit down with Nan Ransohoff, Head of Public Goods at Stripe and a leader behind Frontier, the advanced market commitment helping build the market place for carbon removal. Nan explains why cutting emissions alone won't be enough to meet climate goals, what it will take to scale carbon removal from thousands to trillions of tons, and why governments—not just companies—will ultimately need to create and fund the markets that make it possible. They discuss the most promising carbon removal technologies, the role AI could play in accelerating climate solutions, and what it means to be a "general manager" for challenges that affect all of humanity.

For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

Reid and Aria explore what the coming wave of AI IPOs could mean for the future of technology, investing, and the broader economy. They discuss why public ownership may become an important way for society to participate in AI’s upside, where Reid sees the strongest long-term opportunities across the AI landscape, and why the next generation of software engineers will be defined by managing AI agents. They end the episode examining the rise of AI-generated music, what it means for creativity and copyright, and why AI should be viewed as a tool that expands human expression rather than replaces it. 

To watch Reid’s Pi Day music video: https://www.instagram.com/reel/DV3-Pw8EZ7x/?hl=en

Reid sits down with Microsoft CEO Satya Nadella fresh off Microsoft Build 2026. The conversation goes wide: how AI is reshaping work, business, and society—and why the transformation sweeping through software development today is only a preview of what's coming for all knowledge work. Satya makes the case that human capital and "token capital" are now deeply intertwined, that companies—not just countries—must build their own AI capabilities, and that the organizations best positioned to thrive are those that can leverage their unique expertise inside intelligent systems. Reid and Satya also explore Microsoft's enterprise AI vision, Reid's work with Manas on AI-powered scientific discovery, lessons from past technological revolutions, and why demonstrating real, tangible benefits may be the most important thing the industry can do to earn—and keep—the public's trust.

For more info on the podcast and transcripts of all the episodes, visit
https://www.possible.fm/podcasts/satya/

Before Kanjun Qiu raised $200 million from NVIDIA and others to build reliable AI agents, she was writing high-frequency trading algorithms to pay her way through MIT. Today she leads Imbue, an AI lab unusually focused on power, agency, and what it would take to make AI systems trustworthy by design. In this episode, Reid Hoffman and Aria Finger sit down with Kanjun to explore what it means to truly own your AI tools, not just use them; how to build agents that are systemically trustworthy, not just convincingly so; and why the future of AI may depend as much on moral invention as technical innovation. From meditation and the amygdala to Adam Smith and open-source software, this is a conversation about the deeper architecture of the AI future.

For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

Reid and Aria dig into where AI is creating real, durable value—and where they see it heading to next. Reid shares an inside look at his AI-driven drug discovery work at Manas AI, making the case that medicine could be one of the biggest opportunities in the entire AI landscape. They also explore why AI will likely shift toward a mix of specialized agents and “front doors” rather than a single dominant assistant, how enterprise vs. consumer AI revenue will evolve, and what companies like Anthropic signal about where the real business of AI is taking shape. They also touch on the role of governments in delivering AI-powered public goods, before closing with a candid conversation on political corruption, institutional trust, and why civic courage still matters.