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The Neuro Experience

Louisa Nicola & Pursuit Network
The Neuro Experience
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  • How Women Can Strengthen Their Hearts After Menopause | Dr. Jeremy London
    Every 80 seconds, a woman dies from heart disease — yet most still think cancer is the bigger threat. In this minisode, I sit down with Dr. Jeremy London, board-certified cardiothoracic surgeon, to unpack why women’s cardiovascular risk skyrockets after menopause and how hormones, inflammation, and lifestyle choices all connect. This episode features highlights from our full conversation, which premiered July 24th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=7jbvQRZgb3w Dr. London explains how declining estrogen drives visceral fat, raises cholesterol, and fuels chronic inflammation — creating a “perfect storm” for heart attacks, strokes, and even Alzheimer’s. From estrogen and inflammation to cholesterol, exercise, and sleep — this conversation exposes the real science behind heart and brain health. If you’ve ever wondered how to protect yourself from the #1 killer of women, this episode will change how you think about prevention, hormones, and longevity. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** I’m Louisa Nicola — clinical neurophysiologist  — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Why Women’s Heart Risk Triples After Menopause 00:55 – Estrogen’s Role: Anti-Inflammatory and Protective 01:45 – Weight Gain, Visceral Fat, and Inflammation 02:09 – Cholesterol, LDL, and Rising Risks Post-Menopause 02:38 – The “Perfect Storm” of Metabolic Decline 03:13 – How the Women’s Health Initiative Misled Women on Hormones 03:36 – Estrogen, Brain Health, and Alzheimer’s Connection 04:45 – The #1 Global Killer: Cardiovascular Disease 05:26 – What “Heart Disease” Really Means 06:00 – Cholesterol Explained: HDL, LDL, and Triglycerides 07:37 – Why ApoB Is a More Accurate Marker 09:18 – Plaque Formation and Early Intervention 10:11 – The Study That Reversed Heart Aging by 20 Years 11:24 – VO₂ Max, Zone-5 Training, and Longevity 12:16 – Resistance Training and “Muscle as the Organ of Longevity” 13:09 – Why Consistency Beats Intensity 13:57 – The Sitting Disease and Daily Movement 14:22 – The Power of Nutrition: “Your Body Is the Soil” 15:02 – Whole Foods, Processed Diets, and Alcohol 16:24 – Can Plaque Be Reversed? The Truth 17:11 – Alzheimer’s and Lifestyle: Prevention Starts in Your 30s 18:19 – The Final Pillar: Sleep and Recovery 19:28 – Why Sleep Fuels Brain and Heart Health 20:12 – Which Health Pillar Matters Most for You Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • Why Testosterone is the Missing Link in Women’s Health | ft. Dr. Kelly Casperson
    In this powerful episode, board-certified urologist Dr. Kelly Casperson exposes the gender bias in medicine and reveals why testosterone may be the missing link in women’s mood, motivation, and longevity. One of the few female urologists in the U.S., Dr. Kelly is rewriting the narrative on hormones—explaining why testosterone isn’t “just for men” and why, after 90 years, the FDA still hasn’t approved it for women. Her message is clear: women are not broken. Whether you’re in your 30s, perimenopause, or beyond, this episode will change how you see your biology—and your power. About Dr. Casperson Dr. Kelly Casperson is a urologist, author, speaker, and educator transforming the way women understand their bodies. She empowers women of all ages to embrace sexual health, hormone balance, and intimacy with confidence and curiosity. With humor and candor, she dismantles shame-based myths and teaches one powerful truth: You Are Not Broken. Follow Dr. Kelly Casperson: Instagram: @kellycaspersonmd Podcast: You Are Not Broken Website: https://kellycaspersonmd.com/ *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Go to https://www.troscriptions.com/neuro | Code: NEURO for 10% your first order Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order Timeline: Head to https://timeline.com/neuro to get 20% off Manukora: Head to https://www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. Brickhouse Nutrition: Check out the university study and get 20% off when you use promo code NEURO at https://brickhousenutrition.com. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – From Sex Ed to Menopause 05:15 – FDA Bias & Hormone Approval 07:26 – Redefining HRT as PET (Progesterone, Estrogen, Testosterone) 07:51 – Hormones 101 & Testosterone Misconceptions 10:13 – Perimenopause vs. Stress 11:51 – The “Bricks of the House” Analogy 13:57 – Symptoms of Low Testosterone in Women 15:15 – Lab Values vs. Reality 17:14 – DHEA & Supplementation 20:10 – Emotions on Testosterone 21:23 – Testosterone & Mental Health 22:33 – Vitamin D & Hormone Synergy 23:07 – Debunking Testosterone Myths 26:35 – The “Married-Only” Paradox 27:14 – Perimenopause Misdiagnosis 28:19 – Myth #2 – Masculinization Fear 29:15 – Fertility & Testosterone 30:07 – Pregnancy & Safety 31:01 – Blood Tests Explained 32:41 – Dr. Casperson’s Book & Treatment Guidance 33:24 – Contraindications & Safety 34:06 – Breast-Cancer Data 35:12 – The Menopause Divorce Rate 36:47 – Untreated Menopause & Relationships 39:25 – Testifying at the FDA 41:35 – The Estrogen Box Warning 43:35 – Why the FDA Still Hasn’t Acted 45:59 – Risk Tolerance Gap 46:17 – Systemic Discrimination in Medicine 47:28 – Neurological Protection of Testosterone 48:11 – Alzheimer’s & Hormone Decline 50:11 – Prevention vs. Treatment 52:04 – Brain Receptors & Protection 55:14 – The Brain Literally Eats Itself 57:18 – FDA Hearing Reflection  Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • The New Science That’s Changing Everything We Know About Obesity | ft. Dr. Rocio Salas-Whalen
    Can medications like Ozempic and Mounjaro actually do more than help you lose weight? This minisode features highlights from our full conversation, which premiered October 7th, 2025. Watch the full episode here → https://youtu.be/AcVIiy201H4?si=nlaFL3JnoZHxQVFh Dr. Rocio Salas-Whalen and I explore the difference between GLP-1, GIP, and triple-agonist drugs — and what’s next in obesity medicine, how estrogen changes after 40 drive midsection weight gain and inflammation, why GLP-1s reduce cancer and Alzheimer’s risk through anti-inflammatory and neuroprotective effects and how obesity and insulin resistance impact fertility and PCOS — and how GLP-1s can help.If you’ve ever wondered whether GLP-1s are just “weight loss shots” or a real step forward in metabolic and brain health — this “minisode” is a must-listen. *** Follow Dr. Salas-Whalen: Instagram: @drsalaswhalen TikTok: @drsalaswhalen @strengthmd @thedryrevolution *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 00:04  – The Probiotic GLP-1 Myth 00:19 – The “iPhone Evolution” of GLP-1 Drugs 00:52 – GLP-1 vs GIP vs Triple Agonists Explained 01:24 – Phase 3 Results & Massive Weight Loss Outcomes 01:38 – The Role of Glucagon in Weight Loss 01:56 – Menopause, Estrogen & Midlife Weight Gain0 3:06 – The “Fat Shift” After 40 04:01 – Can You Combine HRT and GLP-1s? 06:17 – “Willpower” vs Biology in Obesity 07:49 – The Genetic and Hereditary Roots of Obesity 08:57 – Breaking the Transgenerational Cycle 09:30 – Thyroid Cancer Myths and GLP-1 Safety 10:49 – GLP-1s and Breast Cancer Prevention 12:06 – Inflammation as the Root of Disease 12:28 – Neuroprotection and Alzheimer’s Prevention 13:17 – GLP-1s, PCOS & Fertility Benefits 13:53 – The Positive Ripple Effect on Mental Health 14:21 – GLP-1s Reduce Alzheimer’s Risk by 33% 14:58 – The Future of Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • How to Rebuild Your Body After 40 | ft. Dr. Stephanie Estima
    Can strength training, sprinting, and nutrition truly transform women’s hormones, metabolism, and longevity? In this episode, Dr. Stephanie Estima — chiropractor, women’s health expert, and founder of The Estima Method — breaks down the science of female physiology, muscle, and midlife health. We cover why walking isn’t enough, how hormones shape muscle and bone, and why protein and strength training are essential “medicine” for women over 35. Expect myth-busting, practical tools, and empowering insights to help you train and live in sync with your biology. About Dr. Stephanie Estima: Dr. Estima began her career in chiropractic care, where she developed a deep interest in neuroscience, biomechanics, and the body’s connection between movement and the brain. After noticing how differently men and women respond to the same health strategies, she became passionate about helping women navigate hormones, metabolism, and midlife health. Where to find Dr. Estima: Instagram: @dr.stephanie.estima Website: https://drstephanieestima.com *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order PUORI: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. AquaTru: Go to https://AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee. Caraway: Visit https://Carawayhome.com/neuro and take an additional 10% off your next purchase. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – Reassessing Hormone Therapy in 2025 04:24 – The Rise of HRT & Social Media Awareness 05:37 – Balancing the Conversation: HRT Pros & Cons 06:42 – Lifestyle Levers That Matter More 08:05 – Why Walking Isn’t Enough Exercise 10:59 – Muscle Quality & Metabolism Explained 12:29 – Type 1 vs. Type 2 Muscle Fibers 16:25 – Glucose, Muscle, and Longevity18:07 – Bone Health & Estrogen 20:33 – The Power of Impact Training 22:28 – How to Build a “Prescription for Health” 24:06 – The Zone 2 Misconception 26:29 – Progressive Overload & The “Weighted Vest” Myth 27:45 – Sample Lower-Body Workout Blueprint 34:03 – Learning Proper Squat Mechanics 35:28 – The Power of Deadlifts & Hip Hinge Movements 36:46 – Glute Bridges & Unilateral Training 38:35 – Nutrition & Midlife Metabolism 39:47 – How Hormones Change Body Composition 42:06 – Sleep, Insulin, and the Estrogen Cascade 43:59 – Strength Training as Hormone Therapy 45:06 – LDL & Visceral Fat Connection 46:04 – Fasting & Female Metabolism 47:17 – Why Aggressive Fasting Backfires for Women 50:53 – The Dark Side of Fasting Culture 53:22 – Practical Guidelines for Eating Windows 54:03 – Under-Fueling & Protein Deficiency in Women 55:09 – Appetite, GLP-1 Drugs & Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • The Overlooked Cancer Benefits of GLP-1 Medications | ft. Dr. Rocio Salas-Whalen
    Can obesity, menopause, and even Alzheimer’s risk be transformed with one class of medications? Triple board-certified endocrinologist Dr. Rocio Salas-Whalen joins The Neuro Experience to unpack the science behind GLP-1 therapies, sustainable weight loss, and hormone health. One of the earliest physicians to adopt GLP-1 treatments, Dr. Salas-Whalen has redefined how obesity and midlife health are managed—showing why weight gain isn’t about “willpower” but biology, inflammation, and longevity. A leader in obesity and hormone medicine, Dr. Salas-Whalen founded StrengthMD and The Dry Revolution, sharing evidence-based wellness insights worldwide. Her upcoming book, Weightless: A Doctor’s Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve, launches Dec 30, 2025 (U.S./Canada) and early 2026 worldwide. Follow Dr. Salas-Whalen: Instagram: @drsalaswhalen TikTok: @drsalaswhalen @strengthmd @thedryrevolution Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Puori Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. Wildgrain For a limited time, Wildgrain is offering our listeners $30 off the first box - PLUS free Croissants in every box - when you go to https://Wildgrain.com/NEURO to start your subscription.  OSEA Get 10% off your first order sitewide with code NEURO at https://OSEAMalibu.com. You’ll get free samples with every order, and free shipping on orders over $50. Honeylove Save 20% Off Honeylove at https://honeylove.com/NEURO. Brickhouse Nutrition Check out the university study and get 20% off when you use promo code NEURO at https://brickhousenutrition.com. Eko Health Get $50 off, plus a FREE custom chest piece cover ($25 value) when you go to https://ekohealth.com/NEURO  *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 01:44 – Dr. Rocio’s Journey into Endocrinology 02:38 – Discovering the First GLP-1 Drug 03:29 – Early Results & FDA Approval 05:00 – GLP-1 101: What It Is + How It Works 06:28 – Natural vs Synthetic GLP-1s 07:09 – GLP-1s & Alzheimer’s Link 08:20 – GLP-1s vs Bariatric Surgery 09:32 – Rewiring Cravings in the Brain 11:24 – Anti-Inflammatory Benefits of GLP-1s 11:24 – Ad 15:19 – Ozempic, Mounjaro & Next-Gen GLP-1s 17:02 – GLP-1s & Women’s Hormones 19:26 – Will You Be on GLP-1 Forever? 21:35 – The Myth of Willpower 23:22 – Breaking Generational Obesity Cycles 24:43 – GLP-1 & Thyroid Cancer Myth 25:55 – Ad27:55 – GLP-1s Reduce Cancer Risk 29:12 – Inflammation & GLP-1s 30:00 – GLP-1s & Fertility (PCOS) 31:27 – GLP-1 Meds Cut Dementia Risk by 33% 32:04 – Muscle Loss on GLP-1s? 33:14 – Muscle: Your Body’s Anti-Inflammatory Organ 34:01 – How to Eat Enough Protein on GLP-1s 35:19 – Tracking Your Body Composition 36:57 – Build Muscle While Losing Weight 37:25 – GLP-1 Side Effects & How to Avoid Them 38:24 – The GPS Method (GLP-1 + Protein + Strength) 38:24 – Ad 41:15 – Exposing “GLP-1 Gummies” & Celeb Hype 41:34 – Microdosing & Maintenance Explained 45:01 – The Emotional Shift in Patients 46:07 – The Future of GLP-1s 48:04 – Ending Chronic Disease Learn more about your ad choices. Visit megaphone.fm/adchoices
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Über The Neuro Experience

This podcast interviews the best experts in the world to bring emerging themes in athletic performance, neurology, sleep physiology and medicine. Louisa regularly consults for technology development companies, professional athletic organizations and consults with the biggest names in NBA, MLB and NFL. Louisa is on the scientific advisory board of Tonal, Hone Health, Klora and Momentous. Find Louisa on Instagram @louisanicola_
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