I receive a lot of health questions about how to remedy various debilitating conditions. One of the more concerning questions I receive frequently is regarding kidney failure. Why is there an epidemic of people with failing kidney function? It comes down to mitochondria dysfunction. Instead of focusing in one one study like most health educators do, my goal with these short shows is to paint broad strokes and cover the entire subject from a birds eye view all the way down to the mitochondrial level. Most importantly, as I cover various health conditions in future episodes, I will focus very heavily on the solutions, citing research and mechanisms to back up each of the proposed supplements or protocols. In the case of the kidneys, it comes down to one protein: mitochondrial transcription factor A, or TFAM. When that critical protein inside mitochondria in your kidneys becomes deficient, energy production falls and tissue function decreases, hence, kidney failure. It always comes back to mitochondria. My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner: https://georgehenner.bandcamp.com Two studies I referenced: Mitochondrial Energetics in the Kidneys https://pmc.ncbi.nlm.nih.gov/articles/PMC5965678/#:~:text=The%20kidney%20is%20one%20of,pressure%20in%20the%20glomeruli5. Loss of Mitochondrial Transcription Factor A (TFAM) in Tubule Cells Causes Renal Failure https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3346980
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33:56
Q&A: What the Anti PUFA Crowd Gets Wrong and Melatonin Dosing for Kids
In this months Q&A episode I answer listener questions including: What are my thoughts on B vitamins? Should we supplement them or get them from food? What is one thing the anti PUFA crowd gets wrong? What are my thoughts on testing omega 3:6 ratio from a dried blood spot sample? What do I think about Dr Matthew Walker on Diary of a CEO Podcast saying "don't supplement large doses of melatonin"? What is a good dose of melatonin for kids? Have I ever taken melatonin to lower anxiety? What do I think about red light and PEMF mats? What is my parasite strategy? What belief or mindset shift created the biggest change in my health? I share why I think vitamin B3 as niacinamide/nicotinamide is one of the most important ones to take, how B3 protects against several different types of cancers, why cigars don't protect from pathogens in oysters, the immense stress lowering effect I felt when I stopped demonizing ascorbic acid, zinc, iron, and vitamin D supplements, and why I think the should observe the diets of deer and elk with the PUFA conversation instead of getting lost in analyzing endless research studies. My website: www.matt-blackburn.com Mitolife products: www.mitolife.co BLACK FRIDAY SALE STARTS MONDAY 11/24 Some of the studies cited in the show: NIacinamide skin cancer study https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/ Niacinamide non hodgkin lymphoma study https://pubmed.ncbi.nlm.nih.gov/37467318/ PUFAs as Anti-Freeze article: https://www.anbg.gov.au/cryptogams/underworld/panel-13/index.html Music by George Henner: https://georgehenner.bandcamp.com
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38:39
My Heavy Metal Detox Strategy
There are many different philosophies in the natural health world about where people should start with their health. Some focus on increasing carbs, some focus on increasing protein, some focus on both. I've heard people in the Ray Peat community say that heavy metal detox is a fad and its not important. For the first half of the show I break down why I think its a great place to start, the biochemistry of exactly how heavy metals harm our cells, how car exhaust contributes to their accumulation, and my thoughts on tracking using HTMA and the Oligoscan. In the second half I talk about solutions, starting with the most affordable to the least affordable. I reference a study looking at the difference in heavy metal excretion of 5 metals using sweating in a sauna or sweating during exercise and which one they found to be more effective. I talk about why I supplement magnesium, zinc, shilajit, and high dose melatonin everyday, and how fiber and high dose zeolite powder can also help. This is by no means a comprehensive show that includes every nuance of heavy metal toxicity. The focus was to make it interesting, digestible, and share actionable steps no matter where you are financially. My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner: https://georgehenner.bandcamp.com
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42:39
Structured Water and Filtration, Finally Combined
Finally, an elegant water filter that actually filters out all contaminants and structures the water at the same time. The Mitolife EZ Flow structured water filter cleans the water in the first four stages, using a combination of a 5 micron sediment filter, KDF55, reverse osmosis, cation resin, and catalytic carbon. Inbetween those effective filtration processes the water is flowing through stages that make the water "ordered" or "coherant". This includes powerful neodynium magnets and 850 nanometer light on a hydrophilic surface, replicating the research of Dr Gerald Pollack and others on forming structured water in the laboratory. Of all the wavelengths of light, infrared light forms it the best. It also goes through elite type 1 unpolished shungite from Russia. This has never been done before in any water filter in the world. Containing 95% + carbon, it is a source of "buckminsterfullerine", or C60, an expensive supplement that people take for anti-aging and detoxification purposes. The remaining content of shungite is similar to shilajit with regards to its mineral content, so it is a natural remineralizer, even if just very small trace amounts. People in Russia have been using shungite to purify collected water in the wild since at least the 1700s, but likely much longer. There are also published studies on shungite's EMF protective effects, and we know that man-made EMFs have the ability to make water less coherant. This is my favorite part about this water filter. Wait, there's more. Then it goes through 100 to 200 vortexes right before it travels up to your spigot. Inbetween draws from the storage tank there is a large build-up of exclusion zone (EZ) water in the infrared light chamber. This is the most exciting product that I've ever released and I am excited for you to experience this water that has a gel-like thicker consistency. Order the filter: https://www.mitolife.co/products/ez-flow-structured-water-filter My website: www.matt-blackburn.com Music by George Henner: https://georgehenner.bandcamp.com
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39:54
Why I Megadose Melatonin Every Night
Dubbed a sleep hormone, melatonin has been branded as a bandaid and short term fix to help you fall asleep. The health influencers told you that its dangerous because it will decrease your body's production if you supplement it. A popular quantum health neurosurgeon once made the ridiculous claim that it changes the shape of your eyeball if you take a melatonin pill, with zero clinical study to back up his claim. It turns out that melatonin is anti-tumor, anti-viral, anti-anxiety, anti-inflammatory, and protects your mitochondria from a myraid of assaults, one of which being electromagnetic field (EMF) exposure. In this episode I address the main three myths that are spread about melatonin and explain why they are wrong. I talk about how most of your melatonin is not made in your pineal gland, how simple melatonin powder is the way to go over rectal or other delivery methods, and I reference a few dozen fascinating studies that talk about the various benefits of supplementing melatonin. Show resources: https://onlinelibrary.wiley.com/doi/10.1111/jpi.70094 https://pmc.ncbi.nlm.nih.gov/articles/PMC7211589/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6017232/ https://www.spandidos-publications.com/10.3892/ijmm.2024.5352 https://pubmed.ncbi.nlm.nih.gov/38214233/ https://pubmed.ncbi.nlm.nih.gov/30192001/ https://api.doris-loh.com/catalog/April_2023_Melatonin_Dosing_Schedule.pdf My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner: https://georgehenner.bandcamp.com
The mitochondria are not just the powerhouse of the cell; they are the engines that run our entire body. If we can remove the obstructions to energy production (calcification, lipofuscin and fibrosis) everything works better, we experience mental clarity and emotional resilience.