🧬 The Rebellious Mindset That Builds Successful Startups | Jimmy Sastra (Part 1/4)
"Maybe because of that experience, we still keep in touch. I feel fortunate that my friends and I built something together back then—even if it started with murals and late nights, it taught me about creativity, risk, and teamwork."
In this episode of The Biotech Startups Podcast, Jimmy Sastra, CEO and co-founder of Monomer Bio, unpacks his global journey from The Netherlands and Japan to transforming lab automation in biotech. Shaped by his father’s engineering legacy at Philips and ASML, Jimmy recalls lessons in creativity, rebellion, and resilience that guided his path from the University of Pennsylvania to a PhD in robotics.
His story reveals how curiosity and systems thinking became the foundation for Monomer Bio’s mission to empower scientists through smarter, automated lab solutions.
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🧬 100 Discovery Interviews Built a $3M Biotech Launchpad at Berkeley | Darren Cooke (Part 4/4)
"If anyone comes to me and says, 'Hey, I’ve got this idea. I think we could do something with it,' I’m like, 'You gotta take the I-Corps class first... it really changes your mindset.'"
In this episode of The Biotech Startups Podcast, Darren Cooke, Interim Chief Innovation & Entrepreneurship Officer and Executive Director of the Life Sciences Entrepreneurship Center at the University of California, Berkeley, reveals how 100 discovery interviews turned a $3 million campus experiment into a powerhouse for biotech innovation.
He shares the creation of Berkeley’s flagship fellows program, the launch of speed teaming and venture grants, and how simple ideas like fostering connection and collaboration transformed campus culture. Darren also reflects on the leadership of Chancellor Rich Lyons and offers candid lessons on perseverance, mentorship, and the art of “showing up.”
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🧬 How to Turn Regulatory Chaos Into Competitive Advantage | Darren Cooke (Part 3/4)
"If you’re not challenging what you’ve always done, you’re not going to move forward or innovate."
In this episode, Darren Cooke, Interim Chief Innovation & Entrepreneurship Officer and Executive Director of the Life Sciences Entrepreneurship Center at the University of California, Berkeley, reveals how he’s navigated the fast-changing world of financial advice by embracing regulatory shifts, championing innovation, and building trust through integrity and open communication, sharing hard-won lessons on personal growth, resilience, and finding new opportunities amid uncertainty and change.
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🧬 Mentors, Networks & IP: Power Moves for Biotech Startup Success | Darren Cooke (Part 2/4)
"If you ever find yourself in a situation where you’re busy and bored, you really should be doing something else."
In this episode, Darren Cooke, Interim Chief Innovation & Entrepreneurship Officer and Executive Director of the Life Sciences Entrepreneurship Center at the University of California, Berkeley, traces his bold path from high-stakes law firm litigation to in-house IP leadership at Bio-Rad Laboratories, eventually launching his own practice to guide biotech startups.
He dives into career pivots, lessons from Berkeley’s entrepreneurial scene, startup investing, and why simply showing up is often the secret to transformative opportunities and growth.
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🧬 Building Berkeley's $1B Innovation Ecosystem | Darren Cooke (Part 1/4)
"If you go down a road and then you realize, Ah, shoot. This was not what I expected, or Why am I doing this? you can do something else. Right? Yeah. Don't sweat it."
In this episode, Jon Chee interviews Darren Cooke, UC Berkeley’s Interim Chief Innovation & Entrepreneurship Officer, whose journey spans engineering cochlear implants, high-stakes patent law, and leading innovation at Berkeley. Darren shares how formative moments, career pivots, and mentorship shaped his approach to entrepreneurship, offering practical wisdom and behind-the-scenes stories from working with Supreme Court Justice Sonia Sotomayor to building collaborative biotech communities.
His multifaceted perspective inspires listeners to embrace change, seek hands-on experiences, and build networks that drive biotech innovation.
The Biotech Startups Podcast by Excedr features weekly conversations with founders, scientists, and investors driving biotech innovation. Host Jon Chee dives into the challenges of building biotech startups, from pre-seed to IPO. New episodes every Monday and Thursday.