AI Was Supposed To Discover New Drugs. Where Are They?
AI is everywhere these days, and though there’s debate about how useful it is, one area where experts think it could be game-changing is scientific research. It promised to be particularly useful for speeding up drug discovery, an expensive and time-consuming process that can take decades. But so far, it hasn’t panned out.The few AI-designed drugs that have made it to clinical trials haven’t been approved, venture capital investment in these efforts has cratered in the last few years, and many startups have shut their doors. So why has it been so hard to make AI-designed drugs? What are the fundamental issues, and what does the future of this research look like?Joining Host Ira Flatow with some answers is Peter Coveney, who studies how chemistry discoveries can be sped up with algorithms and computers.Guest: Dr. Peter Coveney is a professor and director of the Centre for Computational Science at University College London.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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How Math Helps Us Map The World
It’s easy to take maps for granted. After all, most of us have a pretty good map in our pockets at all times, ready to show us how to get anywhere on the globe. But to make a map useful, you have to decide what to keep in and what to leave out—and, most importantly, which mathematical equations to use. Beyond navigating from point A to point B, math and maps come together for a wide variety of things, like working out the most efficient route to deliver packages, calculating the depth of the ocean floor, and more. Host Ira Flatow is joined by Paulina Rowińska, mathematician and author of Mapmatics: A Mathematician's Guide to Navigating the World, to go on a journey through the math at the heart of all kinds of maps. Guest: Dr. Paulina Rowińska is a mathematician, writer, science journalist and author of Mapmatics: A Mathematician's Guide to Navigating the World.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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The Science Of Replacing Body Parts, From Hair To Hearts
It seems like every week, there’s a new headline about some kind of sci-fi-esque organ transplant. Think eyeballs, 3D-printed kidneys, pig hearts.In her new book, Replaceable You: Adventures in Human Anatomy, science writer Mary Roach chronicles the effort to fabricate human body parts—and where that effort sometimes breaks down. Host Flora Lichtman speaks with Roach about everything from hair transplants to 3D-printed hearts, and why our anatomy is so hard to replicate in the first place.Guest: Mary Roach is a science writer and the author of Replaceable You: Adventures in Human Anatomy.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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It’s Not Just You—Bad Food Habits Are Hard To Shake
Remember “The Biggest Loser”—the show where people tried to lose as much weight as quickly as possible for a big cash prize? The premise of the show was that weight loss was about willpower: With enough discipline, anyone can have the body they want.The show’s approach was problematic, but how does its attitude toward weight loss match our current understanding of health and metabolism? The authors of the book Food Intelligence, nutrition scientist Kevin Hall, who studied “Biggest Loser” contestants at the NIH; and science writer Julia Belluz, join Host Flora Lichtman and answer listener questions about nutrition, diet fads, and metabolism.Read an excerpt of Food Intelligence: The Science of How Food Both Nourishes and Harms Us.Guests:Julia Belluz is a science journalist based in Paris.Dr. Kevin Hall is a nutrition scientist and former NIH researcher based in Kensington, Maryland.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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100 Years Later, Quantum Science Is Still Weird
In July 1925, physicist Werner Heisenberg wrote a letter to Wolfgang Pauli sharing his new ideas about what would eventually become known as quantum theory. A hundred years later, that theory has been expanded into a field of science that explains aspects of chemical behavior, has become the basis of a new type of computing, and more. But it’s still really weird, and often counterintuitive. Physicist Chad Orzel joins Host Ira Flatow to celebrate 100 years of quantum science, and separate quantum fact from science fiction.Guest: Dr. Chad Orzel is the R. Gordon Gould Associate Professor of Physics and Astronomy, and chair of the department, at Union College in Schenectady, New York.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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