The Dr. Gabrielle Lyon Show

• Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood

  In this episode, Dr. Alexis Wood, a leading researcher at Baylor College of Medicine, joins me to unpack insights into childhood nutrition, genetics, and cognitive health. Dr. Wood's work bridges genetics, dietary practices, and brain development, highlighting how early-life nutrition can shape lifelong outcomes. We explore cutting-edge research, practical strategies for parents, and the surprising factors influencing children's cognitive and metabolic health.We cover:Why childhood nutrition and genetics have been historically overlooked—and what it means for your family.ADHD and diet: Separating fact from fiction.Debunking popular diet myths: What the research actually says about red meat and processed foods.Cognitive self-regulation: The hidden link between diet, obesity, and ADHD. Precision nutrition & metabolomics: The future is more than one-size-fits-all advice.Whether you're a parent, educator, or health professional, this conversation offers guidance on navigating the complex relationship between nutrition, genetics, and childhood development.Who is Dr. Alexis Wood?Dr. Alexis Wood, Ph.D., F.A.H.A., is an Associate Professor of Pediatrics–Nutrition at Baylor College of Medicine’s USDA/ARS Children’s Nutrition Research Center. Her research integrates genetics, child development, and nutrition, focusing on how genetic factors influence responses to diet and behavior.This episode is brought to you by: PaleoValley - Get 15% off at https://paleovalley.com/drlyonARMRA – Use code DRLYON to get 15% off your first order at https://tryarmra.com/DRLYONOur Place - Use code DRLYON for 10% off sitewide – https://fromourplace.com/DRLYON Timeline - Get 20% off your order of Mitopure - https://timeline.com/LYONFind Dr. Alexis Wood at: Linked In - https://www.linkedin.com/in/lekkiwood/Baylor College of Medicine - https://www.bcm.edu/people-search/alexis-wood-33281USDA/ARS Children's Nutrition Research Center - https://www.bcm.edu/research/research-centers/usda-ars-childrens-nutrition-research-centerAlexis Wood Lab - https://www.bcm.edu/research/faculty-labs/alexis-lekki-wood-labFind Me At: Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient –

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• Are Red Meat Warnings Based on Flawed Science? Dr. David Klurfeld on Nutrition Myths and Industry Bias

  In this episode, I sit down with Dr. David Klurfeld—longtime USDA scientist and one of the few insiders to publicly challenge the WHO's classification of red meat as a carcinogen. We go deep into the flawed evidence behind the infamous 2015 IARC report, why nutritional epidemiology often fails to prove causality, and how a small group of researchers helped shape global policy with low-quality science. If you've ever felt confused about meat, saturated fat, or dietary guidelines, this conversation will help you think critically about what “counts” as evidence—and who gets to decide. We cover:Dr. Klurfeld’s personal journey and lessons from a career in public healthWhy the 2015 IARC red meat classification was based on weak and inconsistent evidenceHow observational studies and “allegiance bias” mislead nutrition scienceThe politics of dietary guidelines and the role of the USDA and WHOWhat the media got wrong—and why red meat remains a nutrient-dense foodWhether you're a clinician, dietitian, or simply trying to make better nutrition decisions, this episode is a powerful reminder that bias, groupthink and weak data can distort science and mislead the public. We need to be discerning about the nutrition and health advice we follow. Who is Dr. David Klurfeld?Dr. David Klurfeld is a nutritional scientist and former National Program Leader for Human Nutrition at the USDA’s Agricultural Research Service. He also served as Professor and Chair of Nutrition and Food Science at Wayne State University and Associate Editor of The American Journal of Clinical Nutrition. He has authored more than 200 scientific publications and was one of 22 experts invited to the 2015 IARC working group on red meat and cancer. He is a longtime advocate for scientific integrity in public health policy.This episode is brought to you by: LMNT- Free Sample Pack with any purchase, visit https://DrinkLMNT.com/DRLYONTimeline - Get 20% off your order of Mitopure - https://timeline.com/LYONMUD\WTR - Use code DRLYON to get up to 43% off your starter kit - https://mudwtr.com/DRLYONNeeded - Use code DRLYON for 20% off your first order - https://thisisneeded.com Find Dr. David Klurfeld at: Indiana University Bloomington - https://publichealth.indiana.edu/about/directory/David-Klurfeld-dmklurfe.html Google Scholar - https://scholar.google.ca/citations?user=Ym5Og20AAAAJ&hl=en LinkedIn - https://www.linkedin.com/in/david-klurfeld-812845209/ Find me at:Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube:

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  1:49:26
• Why Men’s Fertility Is Declining: The Truth About Testosterone | Dr. Larry Lipshultz

  Dr. Larry Lipshultz. is one of the world's leading experts in men's reproductive health. In this week's episode, we discuss testosterone therapy, male fertility, and the hidden environmental factors threatening men’s health. Dr. Lipshultz shares groundbreaking insights into why male fertility is declining, common myths surrounding testosterone and prostate cancer, and innovative strategies to safely enhance men's reproductive and overall health.We cover: The alarming 50% drop in male fertility since the 1980s—and what’s driving itTestosterone therapy myths: prostate cancer, fertility, and what’s actually truePractical treatments for restoring fertility while on testosterone therapyAnabolic agents: risks, benefits, and smart usePersonalized, patient-centered care to optimize male reproductive and overall healthIf you care about men's health, fertility, or hormone optimization, this conversation is a must-listen.Who is Dr. Larry Lipshultz? Dr. Lipshultz’s research focuses on male reproductive dysfunction, testosterone therapy, cardiovascular risk, and the genetics of infertility. He has pioneered innovations in testicular sperm extraction, vasectomy reversal, and testosterone optimization therapies. With over 460 peer-reviewed publications and as co-author of a foundational textbook on andrology, his contributions have significantly enhanced diagnostic approaches in male infertility. An early recipient of the American Urological Association Research Scholar award, he advocates for integrative andrologic health as a foundation for lifelong wellness.This episode is brought to you by: Puori - Get 20% off sitewide with Code DRLYON - https://Puori.com/DRLYONCozy Earth - Use code DRLYON for up to 40% off - https://cozyearth.comTimeline - Get 20% off your order of Mitopure - https://timeline.com/LYONManukora - Get $25 off the Starter Kit - https://manukora.com/DRLYONFind Dr. Lipshultz at: Website - https://www.larrylipshultz.com/Baylor College of Medicine - https://www.bcm.edu/people-search/larry-lipshultz-25437 LinkedIn - https://www.linkedin.com/in/larry-lipshultz-md-93977344/ Find Me At: Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter –

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  1:47:11
• How to Train Your Mind: Ancient Wisdom, Modern Science, and the Mindset of Excellence | Brian Johnson

  What if your biggest challenge isn’t motivation but missing structure? In this episode, I sit down with Brian Johnson to unpack the science and philosophy of lasting behavior change. We explore the power of ancient wisdom, stoicism, and the neuroscience of excellence, and why most wellness apps fail to deliver real transformation.Brian shares his personal journey from startup success to creating a global movement around character, discipline, and identity-based habits. We talk about the science of anti-fragility, how muscle mirrors virtue, and why the gap between who you are and who you could be is the true source of suffering. Whether you're a high performer or someone who wants to stop breaking promises to yourself, this conversation will help you build the structure to show up as your best—no matter the circumstance.What You’ll Learn:Why most behavior change fails—and what the science says worksThe philosophy of Areté: how to close the gap between potential and actionHow ancient stoicism aligns with modern recovery, resilience, and muscleWhy building muscle is a metaphor (and mechanism) for building characterThe true definition of anti-fragility—and how to train itIf you're ready to bridge the gap between knowing and doing, this episode is the roadmap you've been looking for. Who is Brian Johnson? Brian Johnson has spent half of the last 25 years as a Founder/CEO and the other half as a Philosopher. As a Founder/CEO, he’s made crowdfunding history and built and sold two market-leading social platforms. As a Philosopher, he created Philosopher’s Notes, wrote the bestselling book Areté: Activate Your Heroic Potential, and developed a protocol integrating ancient wisdom, modern science, and practical tools that has been scientifically proven to help people change their lives. Brian is featured in the documentary Finding Joe on the modern Hero’s Journey and has trained some of the world’s most elite performers. He lives in the country outside of Austin with his wife and two kids and is all in on fulfilling Heroic’s mission to help create a more noble and virtuous world in which 51% of humanity is flourishing by 2051.This episode is brought to you by:LMNT- Free Sample Pack with any purchase, visit https://DrinkLMNT.com/DRLYONAG1 - FREE bottle of AG D3K2, an AG1 Welcome Kit + 5 travel packs with your first order – https://drinkAG1.com/DRLYONOneSkin - Use Code DRLYON for 15% off OneSkin – https:// www.oneskin.coTimeline - 20% off your order of Mitopure visit https://timeline.com/LYONFind Brian Johnson at:Learn more about Brian Johnson and Heroic and get some free content just for my listeners: heroic.us/drlyon Tiktok: https://www.tiktok.com/@heroicbrianInstagram: https://www.instagram.com/heroicbrian/Facebook: https://www.facebook.com/heroicbrian/Linkedin: https://www.linkedin.com/in/heroicbrian/YouTube:

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  1:15:33
• Understanding Heart Rate Variability: Improving Your Health & Performance | Joel Jamieson

  When it comes to performance, more isn’t always better. In this episode, I sit down with conditioning expert Joel Jamieson to explore the science of recovery, aerobic fitness, and how to use heart rate variability (HRV) to train smarter. They dive into why elite athletes recover so quickly, the long-term value of zone 2 training, and how HRV reflects your resilience—not just your readiness. Joel shares lessons from two decades of working with fighters, Olympians, and NFL players, along with powerful insights from his own cardiovascular health journey. Whether you’re a high performer or simply want to live longer and stronger, this episode is packed with practical takeaways.In this episode, you’ll learn:What HRV actually tells you—and what it doesn’tWhy aerobic fitness is one of the strongest drivers of recovery and longevityThe surprising downside of too much strength trainingHow to monitor training load and avoid overtrainingWhy lifestyle stress matters more than your workoutThis episode will change the way you think about training—and reveal why recovery deserves a central role in your performance strategy.Who is Joel Jamieson? Joel Jamieson is a leading coach and educator in recovery-based training and heart rate variability (HRV). With over 20 years of experience working with professional athletes, including NFL players and world champion fighters, he’s known for translating complex performance science into practical tools. He’s the creator of Morpheus, a system that helps tailor training to daily recovery status, and the founder of 8WeeksOut, a resource for conditioning and performance education.This episode is brought to you by:Puori - Code DRYLYON to get 20% off sitewide - https://Puori.com/DRLYONMUD\WTR - Code DRLYON to get up to 43% off your starter kit - https://mudwtr.com/DRLYONBON CHARGE - Code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONARMRA - Code DRLYON to get 15% off your first order - https://tryarmra.com/DRLYON Find Joel Jamieson at:Instagram: @coachjoeljamieson8WeeksOut: https://8weeksout.com/Morpheus: https://trainwithmorpheus.com/Find Me At: Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter –

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  1:59:13

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