PsychRounds: The Psychiatry Podcast

Today, we welcome back a former guest, Dr. Mark Ruffalo, and joining him is his colleague and co-author, Dr. Ronald Pies. We will be discussing their recently published article, The Need For A Validity-Based Hierarchy In DSM-6.

Article: https://pubmed.ncbi.nlm.nih.gov/42908074/
Dr. Ruffalo Website: https://www.drruffalo.com/
Dr. Pies Psychiatric Times Profile: https://www.psychiatrictimes.com/authors/ronald-w-pies-md

Today, we're covering the recent FDA approval of a new Olanzapine long-acting injectable - Weltruza.

References:
https://pubmed.ncbi.nlm.nih.gov/41632432/
https://pubmed.ncbi.nlm.nih.gov/42198294/
https://www.tevapharm.com/news-and-media/latest-news/new-long-term-safety-data-from-the-completed-phase-3-solaris-trial-support-the-potential-of-olanzapine-la/

Welcome back, everyone! We’re back after PRITE, and today we’re discussing pharmacogenetic testing.

Today, we will discuss GLP-1's and the emerging use of this class of medications in psychiatry.

Sources:
https://pubmed.ncbi.nlm.nih.gov/42247271/
https://pmc.ncbi.nlm.nih.gov/articles/PMC11441540/
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2838205
https://pubmed.ncbi.nlm.nih.gov/42070571
https://pubmed.ncbi.nlm.nih.gov/41806782/

We resume our landmark studies series looking at the pivotal study in Major Depressive Disorder (MDD), The STAR*D (Sequenced Treatment Alternatives to Relieve Depression) trial.

References:
https://pubmed.ncbi.nlm.nih.gov/12778843/
https://pubmed.ncbi.nlm.nih.gov/19880458/
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482026
https://pubmed.ncbi.nlm.nih.gov/15061154/
https://pubmed.ncbi.nlm.nih.gov/20370962/
https://pubmed.ncbi.nlm.nih.gov/37491091/