Welcome one and all to another enlightening episode of The Empowering Neurologist. Joining us is Dr. Ray Dorsey, Professor of Neurology at the University of Rochester, a stalwart advocate for Parkinson's disease, and a renowned researcher in the field. With a profound belief in the power of awareness and knowledge, Dr. Dorsey dedicates his life to a cause that is impacting millions globally. He stands at the forefront of the fight against Parkinson's disease, a fight that is becoming increasingly critical as we see a staggering rise in the incidence of this condition.   Dr. Dorsey is not just an accomplished physician but also an engaging author. His groundbreaking book, Ending Parkinson’s Disease, is a critical exploration that sheds light on this global health crisis. It offers an enlightening perspective on Parkinson's disease and, so importantly as we discuss in this episode, its modifiable risk factors, raising consciousness and hope about this life-altering condition.   His book is an earnest appeal to policymakers, researchers, physicians, and the general public to recognize the escalating crisis and join the battle to end Parkinson's. It also serves as a testament to his belief in our collective ability to mitigate this crisis, beginning with understanding the risk factors that we can change.   We delve into the comprehensive world of Ending Parkinson’s Disease, discuss the modifiable risk factors, and explore ways to curb the skyrocketing incidences of Parkinson's. It is our shared responsibility, and understanding is the first step.   So, please enjoy this fascinating interview.   ====   Timestamps   0:00 Intro 0:50 Rise in Parkinson’s 3:20 MPTP 8:10 Trichloroethylene (TCE) 13:14 Call to Action 16:19 Prevention of Parkinson’s 32:00 Caffeine and Smoking 37:25 Head Trauma 39:27 Conclusion     Dr. Ray Dorsey is the David M. Levy Professor of Neurology at the University of Rochester.  Ray is working to identify and eliminate the root causes of Parkinson’s disease.  His research on brain diseases and digital health has been published in leading academic journals and featured in multiple news outlets.  In 2020, Ray and his colleagues wrote Ending Parkinson’s Disease, a book that provides a prescription for ending the world’s fastest growing brain disease.   Ray previously directed the movement disorders division and neurology telemedicine at Johns Hopkins and worked as a consultant for McKinsey & Company. In 2015, the White House recognized him as a “Champion for Change” for Parkinson’s disease.   Dr. Dorsey is the co-author of the book Ending Parkinson's Disease - A Prescription for Action available at retailers everywhere. The authors are all devoting their proceeds to efforts to prevent and end Parkinson’s. If you cannot afford a copy, they will send you one for free. You can just email them at [email protected] with your preferred mailing address. They are also happy to hear their stories or field questions that you may have.   ___________________________   Instagram: https://www.instagram.com/davidperlmutter/   Website: https://www.drperlmutter.com/   Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1See omnystudio.com/listener for privacy information.

In this installment of The Empowering Neurologist we are privileged to welcome Dr. Nathan Bryan, a trailblazer in the realm of biomedical research, with a specific focus on the life-sustaining molecule, nitric oxide.  As a globally recognized pioneer in nitric oxide biochemistry and physiology, Dr. Bryan’s contributions have significantly shifted our understanding of the role of nitric oxide in overall human health. I had the privilege of attending a lecture given by Dr. Bryan recently and learned that he is a tenacious advocate for understanding nitric oxide not as a mere molecule, but as a vital bioactive substance with a profound influence on numerous physiological processes. His extensive research has elucidated nitric oxide's pivotal roles in areas like maintaining vascular health, bolstering the immune system, and regulating the cardiovascular system. These insights have been instrumental in revolutionizing therapeutic strategies and disease management methods. In a world beset by increasing health challenges, understanding the critical role of nitric oxide is paramount. This molecule is the very fulcrum of our well-being, influencing how cells communicate and interact, determining disease resistance, and even dictating our longevity. Dr. Bryan's invaluable work unveils the importance of maintaining nitric oxide balance for optimum health and wellbeing. And interestingly, the nitric oxide story fully dovetails with our work in the area of uric acid as we discuss. I’m certain you will be fascinated by this interview as we do a deep dive into the world of nitric oxide with Dr. Bryan, whose pioneering work continues to enlighten us on the intricate mechanisms that drive human health. This conversation promises to challenge preconceived notions, inspire new health perspectives, and fundamentally reshape how we approach wellness in the 21st century.   Timestamps   0:00 Intro 3:14 Nitric Oxide 5:29 Measuring Nitric Oxide “interestingly” 8:36 Oral Health and Nitric Oxide 15:02 Acid Blocking Drugs 18:00 Dietary Sources of Nitrates 19:55 Oxygen Availability 23:14 MTFHR 27:46 Age and Nitric Oxide 30:42 Viagra 35:46 Wound Healing 43:27 Latest Findings 46:27 Nathan’s Book Release 48:23 Conclusion   ====   Dr. Bryan earned his undergraduate Bachelor of Science degree in Biochemistry from the University of Texas at Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport where he was the recipient of the Dean’s Award for Excellence in Research.  He pursued his post-doctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute.  After a two year post-doctoral fellowship, in 2006 Dr. Bryan was recruited to join faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology.  Dr. Bryan has been involved in nitric oxide research for the past 20 years and has made many seminal discoveries in the field.  His many seminal discoveries have resulted dozens of issued US and International patents and the product technology resulting from his discoveries and inventions has improved patient care worldwide.  Dr. Bryan is a successful entrepreneur and Founder of HumanN, Inc, Pneuma Nitric Oxide, LLC, Nitric Oxide Innovations, LLC and Bryan Nitriceuticals, LLC.  His product technology is responsible for hundreds of millions of product sales worldwide.  Most recently, Dr. Bryan serves as Founder and CEO of Nitric Oxide Innovations, LLC, a privately-held, clinical-stage biopharmaceutical company that is actively engaged in the discovery and development of nitric oxide based therapies.  Their lead drug candidate NOviricid is currently in phase 3 clinical trials for the treatment of COVID19 in African Americans and Hispanics.  Dr. Bryan is an international leader in molecular medicine and nitric oxide biochemistry.     www.N1O1.com www.drnathansbryan.com www.NO2U.com www.nitricoxideinnovations.com   ___________________________ Instagram: https://www.instagram.com/davidperlmutter/   Website: https://www.drperlmutter.com/   Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1See omnystudio.com/listener for privacy information.

So-called "long Covid" is turning out to be a devastating condition for an incredibly large number of individuals around the world. It's been estimated that as many as 200 million people globally are suffering from this condition. And as many as 30 percent of Covid-19 survivors still experience symptoms long after their acute illness has passed, with cognitive and mental health problems especially prominent.    From the publisher of Clearing the Fog: For long haulers, this struggle with Long Covid has irrevocably changed their lives. Many have lost their ability to work, attend school, and look after their children. They often feel misunderstood and dismissed by others. Their once-full lives are now filled only with doctors' appointments that seem more and more futile.   In Clearing the Fog, neuropsychologist Dr. James C. Jackson offers people suffering from Long Covid and their families a roadmap to help them manage their “new normal.” Focusing on cognitive impairment and mental health issues, he shows readers:   - The ways in which they can manifest and disrupt - Suggestions for how and when to seek professional evaluations - Science-based treatment options and strategies, - Information on navigating health care systems and disability insurance - Validation and hope as patients wrestle with their new diagnosis   In addition, Dr. Jackson shares his own experience with chronic illness, relating to long haulers with vulnerability and compassion.   Through moving stories as well as hands-on guidance, Clearing the Fog will help long haulers understand their current situation while offering multiple ways to address it, make sense of it, and move through it with the goal of thriving instead of merely surviving.    In this interview with Dr. Jackson, we will explore the following questions, and a lot more:   What do we know about the cognitive and mental health consequences of Long Covid?   What areas of cognition are impacted in Long Covid survivors?   How does cognitive impairment impact the daily lives and the careers of those with Long Covid?   What treatments have you found effective for Long Covid survivors and what does the research say?   What do we know about the benefits of cognitive rehabilitation?   Are there ways to leverage the neuroplasticity that Long Covid survivors have?   What role does acceptance play in coping effectively with Long Covid   ___________________________   TIMESTAMPS: 0:00 Intro 2:41 Cognitive Complaints 7:29 No Quick Fix 13:22 Cognition vs. Function Testing 17:58 The Ideal Long COVID Team 20:13 Plasticity and Recovery 22:40 Personalization in Treatment 25:08 Goal Management Training 29:16 Brain Training Apps 31:16 Anxiety and Depression 34:04 Restorative Sleep 35:39 Post Traumatic Growth 38:26 Practical Strategies 40:55 Conclusion   ___________________________   Instagram: https://www.instagram.com/davidperlmutter/   Website: https://www.drperlmutter.com/   Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1See omnystudio.com/listener for privacy information.

Health and happiness go hand in hand, and who couldn’t use a little more of both these days? This is from the back cover of an exciting new book, *The Joy of Well-being,* by Colleen and Jason Wachob. This is such a wonderful guide that, lovingly, gifts us the tools to more fully enjoy the ride, and become healthier in the process!   Colleen Wachob is the co-founder and co-CEO at mindbodygreen, the leading independent media brand dedicated to well-being with 15 million monthly unique visitors. She graduated from Stanford University with degrees in international relations and Spanish. She spent ten years working at Fortune 500 companies including Gap, Walmart, and Amazon before devoting her life’s work to mindbodygreen. Colleen has been a speaker at Fortune 500 companies and numerous trade conferences on well-being trends. Her new passion that brings her joy is pickleball.   Jason Wachob is the founder and co-CEO of mindbodygreen, the leading independent media brand dedicated to well-being with 15 million monthly unique visitors. He is also the host of the popular mindbodygreen podcast and the bestselling author of Wellth: How I Learned to Build a Life, Not a Resume. He has been featured in the New York Times, Entrepreneur, Forbes, Fast Company, Business Insider, and Vogue, and has a BA in history from Columbia University, where he played varsity basketball for four years. He lives with his wife, co-founder, and co-CEO Colleen, in Miami with their daughters, Ellie and Grace. In his spare time he loves walking to get hot black coffee.   This is a really warm and feel-good interview, Hope you all enjoy! ___________________________   TIMESTAMPS   0:00 Intro 4:28 The Journey of Well-Being 15:35 Wellness vs. Well-Being 19:30 Navigating Too Much Information 23:46 New Breathing Discoveries 28:39 Healthy Sleep Habits 33:56 Too Much Monitoring 39:22 Health Pile Up 41:55 The Well-being Way 47:50 Moving Out of NYC 50:44 Conclusion   ___________________________ Instagram: https://www.instagram.com/davidperlmutter/   Website: https://www.drperlmutter.com/   Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1See omnystudio.com/listener for privacy information.

I'll never forget back in medical school that we were told that the brain was "terminally differentiated.” This means that brain cells were what they were, and could never be regenerated. As such, when a person had a stroke or brain injury, that was pretty much the end. There would be no improvement. That understanding stands in stark contrast to what we have observed. Clearly, stroke patient can and do improve. And, it turns out, that this improvement can be enhanced with a type of therapy that applies pure oxygen under pressure to the patient. This increased oxygen in the brain does some wonderful things including, importantly, enhancing the growth of new brain cells. What a concept. I have a long experience with hyperbaric oxygen therapy, having founded one of the countries largest hyperbaric centers. Much of the data upon which we relied came from researchers in Israel who were and continue to do cutting edge science demonstrating the profound effectiveness of hyperbaric oxygen therapy as it relates to stroke recovery. Nowadays, improvements in brain functionality can actually be visualized with state of the art brain imaging equipment. Today, on the Empowering Neurologist, I have the great honor of interviewing Dr. Shai Efrati, one of the global leaders in the application of hyperbaric oxygen therapy for the treatment of stroke. Dr. Efrati is Founder and Director of the world-leading Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, where he also serves as Director of Research and Development and Head of Nephrology. Dr. Efrati’s research focuses on novel aspects of hyperbaric medicine and brain rehabilitation. He is a professor at the Sackler School of Medicine and the Sagol School of Neuroscience in Tel Aviv University. Since 2008, he has served as Chairman of the Israeli Society for Diving and Hyperbaric Medicine. Importantly, Dr. Efrati is now associated with the Aviv Clinic, which is not only offering hyperbaric oxygen therapy, but a far more comprehensive approach for stroke recovery And fortunately, the clinic is located in the Villages, just outside of Orlando Florida. Please enjoy this fascinating deep dive into the benefits of hyperbaric oxygen therapy, especially as it relates to stroke recovery.   TIMESTAMPS: 0:00 Intro 1:21 Hyperbaric Oxygen Therapy 10:13 How Oxygen Therapy Works 14:37 Brain Cell Regeneration 16:43 Stroke Treatment 22:34 Scaling This Treatment 25:36 The Aviv Clinic 29:14 Vascular Dementia 35:43 Autism 40:39 Consult A Professional 42:33 Conclusion ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1See omnystudio.com/listener for privacy information.